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Melanotan II 10 mg – Jolt Peptides vial and box
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Melanotan II 10 mg

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Analytical documentation

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What Melanotan II is

Melanotan II (MT-2) is a synthetic cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone (α-MSH). It binds to several melanocortin receptors (MC1R, MC3R, MC4R) and was originally developed in the 1990s at the University of Arizona. It is not an approved medicinal product.

What is studied with Melanotan II

  • Skin pigmentation – stimulation of melanin production via the MC1 receptor.
  • Melanocortin signalling – effects mediated by MC3/MC4 receptors in the central nervous system.
  • Appetite and energy balance – MC4 receptor pathways in animal models.
  • Related compounds – research on Melanotan II led to the more selective peptide bremelanotide.

Reconstitution and storage

The vial contains 10 mg. Dissolving it in 2.0 ml of solvent gives 5 mg/ml, i.e. 5 µg per microlitre. The reconstitution calculator works out other volumes; for reconstitution we offer bacteriostatic water.

Store the lyophilisate dry and dark, long term at −20 °C. Keep the solution at 2–8 °C, divide it into aliquots for longer storage and avoid repeated thawing. More in how to store and ship peptides.

For laboratory research only. Not for human consumption.

Specifications

Molecular profile – sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Molecular formula

C50H69N15O9

Molecular weight

1024.2 g/mol

CAS

121062-08-6

Form

Lyophilized powder, 10 mg

Peptides in transit

We ship lyophilized peptides in glass vials by standard shipping; they do not need refrigeration. Short temperature fluctuations in transit do not reduce their quality, and the lyophilized form stays stable for several weeks even in summer temperatures.

Storing lyophilized peptides

Store lyophilized peptides in a dry place, protected from light and moisture. We generally recommend these conditions:

  • Room temperature (15–25 °C): up to 3 months
  • In the fridge (2–8 °C): up to 6 months
  • In the freezer (−20 °C and below): 3–5 years (recommended for long-term storage)

After taking the vial out of the fridge or freezer, let it warm to room temperature.

Storing reconstituted peptides

Peptide solutions are generally less stable after reconstitution than the lyophilized form, so keep them cold whenever possible. We generally recommend these conditions:

  • Room temperature (15–25 °C): not recommended long term
  • In the fridge (2–8 °C): usually 4–8 weeks
  • In the freezer (−20 °C and below): up to 3–4 months

To keep the peptide intact, avoid repeated freezing and thawing, which can speed up its degradation.

Important:

Most manufacturers recommend using reconstituted peptides stored at 2–8 °C within 4 weeks. This recommendation is deliberately cautious and may not reflect the actual chemical stability of every peptide. In our own stability tests, many peptides dissolved in bacteriostatic water showed no measurable degradation after 12 weeks in the fridge. Stability depends strongly on the sequence and formulation, however, so this result cannot be generalised to all peptides without more data.

Scientific sources and citations will appear here.

Every new formulation is based on data from reliable scientific sources:

PubChem chemical database logo
Science journal logo
Janoshik independent laboratory logo
LiquiLabs independent laboratory logo
Logo PubMed (National Library of Medicine)
PubChem chemical database logo
Science journal logo
Janoshik independent laboratory logo
LiquiLabs independent laboratory logo
Logo PubMed (National Library of Medicine)

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